Somatostatin system: molecular mechanisms regulating anterior pituitary hormones

Pituitary Hormones: Posterior Pituitary & Anterior Pituitary

The pituitary gland, also known as hypophysis, is a small pea-sized gland about 1 cm in diameter and 0.5 to 1 gram in weight. The pituitary gland resides in a small bony cavity situated at the base of the brain, known as sella turcica, and a pituitary stalk (infundibulum) maintains a connection between the pituitary gland and hypothalamus. The secretion of hormones by the pituitary gland is und...

Pituitary Hormones: Posterior Pituitary & Anterior Pituitary

The pituitary gland, also known as hypophysis, is a small pea-sized gland about 1 cm in diameter and 0.5 to 1 gram in weight. The pituitary gland resides in a small bony cavity situated at the base of the brain, known as sella turcica, and a pituitary stalk (infundibulum) maintains a connection between the pituitary gland and hypothalamus. The secretion of hormones by the pituitary gland is und...

Purification of anterior pituitary and hypothalamic hormones.

Pure preparations of pituitary and hypothalamic hormones are needed mainly for (1) their chemical characterisation, which increases our understanding of their biochemistry and makes their synthesis possible; (2) replacement therapy, in which contamination with other pituitary hormones is undesirable; and (3) the development of specific diagnostic assays. Pituitary hormones were first isolated f...

The hormones of the anterior pituitary.

Mechanisms regulating somatostatin release and somatostatin-induced acetylcholine release from the myenteric plexus.

The present studies were performed to characterize the molecular form(s) of somatostatin present in the myenteric plexus and to examine some aspects of the regulatory mechanisms underlying somatostatin release and somatostatin-induced release of acetylcholine from this tissue. We observed the following: (1) Somatostatin-like immunoreactivity (SLI) is present in the myenteric plexus of the guine...